{ "_id": "6a1fefbcb401979e73441bb8", "Package": "Haplin", "Title": "Analyzing Case-Parent Triad and/or Case-Control Data with SNP\nHaplotypes", "Version": "7.3.2", "Date": "2024-08-16", "Type": "Package", "Authors@R": "c( person(\"Hakon K.\", \"Gjessing\", email = \"hakon.gjessing@uib.no\",\nrole = c(\"aut\", \"cre\")),\nperson(\"Miriam\", \"Gjerdevik\", role = \"ctb\", comment = \"functions 'lineByLine', 'cbindFiles', 'rbindFiles', 'snpPower', 'snpSampleSize', 'hapSim', 'hapRun', 'hapPower', 'hapPowerAsymp', and 'hapRelEff'\"),\nperson(\"Julia\", \"Romanowska\", role = \"ctb\",\ncomment = c( ORCID = \"0000-0001-6733-1953\", \"new data format, parallelisation, new documentation\") ),\nperson(\"Oivind\", \"Skare\", role = \"ctb\", comment = \"TDT tests\")\n)", "Maintainer": "Hakon K. Gjessing ", "Description": "Performs genetic association analyses of case-parent triad\n(trio) data with multiple markers. It can also incorporate\ncomplete or incomplete control triads, for instance independent\ncontrol children. Estimation is based on haplotypes, for\ninstance SNP haplotypes, even though phase is not known from\nthe genetic data. 'Haplin' estimates relative risk (RR +\nconf.int.) and p-value associated with each haplotype. It uses\nmaximum likelihood estimation to make optimal use of data from\ntriads with missing genotypic data, for instance if some SNPs\nhas not been typed for some individuals. 'Haplin' also allows\nestimation of effects of maternal haplotypes and\nparent-of-origin effects, particularly appropriate in perinatal\nepidemiology. 'Haplin' allows special models, like\nX-inactivation, to be fitted on the X-chromosome. A GxE\nanalysis allows testing interactions between environment and\nall estimated genetic effects. The models were originally\ndescribed in \"Gjessing HK and Lie RT. Case-parent triads:\nEstimating single- and double-dose effects of fetal and\nmaternal disease gene haplotypes. Annals of Human Genetics\n(2006) 70, pp. 382-396\".", "License": "GPL (>= 2)", "URL": "https://haplin.bitbucket.io", "VignetteBuilder": "knitr", "RoxygenNote": "7.3.1", "BuildVignettes": "yes", "NeedsCompilation": "yes", "Packaged": { "Date": "2026-06-03 09:00:46 UTC", "User": "root" }, "Author": "Hakon K. Gjessing [aut, cre], Miriam Gjerdevik [ctb] (functions\n'lineByLine', 'cbindFiles', 'rbindFiles', 'snpPower',\n'snpSampleSize', 'hapSim', 'hapRun', 'hapPower',\n'hapPowerAsymp', and 'hapRelEff'), Julia Romanowska [ctb]\n(, new data format,\nparallelisation, new documentation), Oivind Skare [ctb] (TDT\ntests)", "Repository": "https://hkgjess.r-universe.dev", "Date/Publication": "2024-08-21 02:46:41 UTC", "RemoteUrl": "https://github.com/cran/Haplin", "RemoteRef": "HEAD", "RemoteSha": "91faded5cf91709d4e53f5ff73fa6b6c0e712d39", "MD5sum": "7c367fd63aa61ec94b4d6bceb5b43ee3", "_user": "hkgjess", "_type": "src", "_file": "Haplin_7.3.2.tar.gz", "_fileid": "7e57e8e1b5acfa7ff43b50d651f1fc10a2965540f6ca00bcd3b959e4941fcc95", "_filesize": 3543676, "_sha256": "7e57e8e1b5acfa7ff43b50d651f1fc10a2965540f6ca00bcd3b959e4941fcc95", "_created": "2026-06-03T09:00:46.000Z", "_published": "2026-06-03T09:11:24.421Z", "_distro": "noble", "_jobs": [ { "job": 79258530214, "time": 186, "config": "linux-devel-arm64", "r": "4.7.0", "check": "OK", "artifact": "7380211869" }, { "job": 79258530223, "time": 194, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "7380213722" }, { "job": 79258530197, "time": 172, "config": "linux-release-arm64", "r": "4.6.0", "check": "OK", "artifact": "7380206536" }, { "job": 79258530256, "time": 199, "config": "linux-release-x86_64", "r": "4.6.0", "check": "OK", "artifact": "7380215150" }, { "job": 79258530304, "time": 317, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "OK", "artifact": "7380291359" }, { "job": 79258530306, "time": 424, "config": "macos-oldrel-x86_64", "r": "4.5.3", "check": "OK", "artifact": "7380335488" }, { "job": 79258530278, "time": 227, "config": "macos-release-arm64", "r": "4.6.0", "check": "OK", "artifact": "7380218236" }, { "job": 79258530294, "time": 333, "config": "macos-release-x86_64", "r": "4.6.0", "check": "OK", "artifact": "7380280351" }, { "job": 79257711190, "time": 281, "config": "source", "r": "4.6.0", "check": "OK", "artifact": "7380144222" }, { "job": 79258530217, "time": 120, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "7380188519" }, { "job": 79258530224, "time": 248, "config": "windows-devel", "r": "4.7.0", "check": "OK", "artifact": "7380232536" }, { "job": 79258530258, "time": 199, "config": "windows-oldrel", "r": "4.5.3", "check": "OK", "artifact": "7380215158" }, { "job": 79258530307, "time": 195, "config": "windows-release", "r": "4.6.0", "check": "OK", "artifact": "7380213641" } ], "_buildurl": "https://github.com/r-universe/hkgjess/actions/runs/26874385638", "_status": "success", "_host": "GitHub-Actions", "_upstream": "https://github.com/cran/Haplin", "_commit": { "id": "91faded5cf91709d4e53f5ff73fa6b6c0e712d39", "author": "Hakon K. 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